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Friday, September 4, 2020

A Covid19 vax by November 1st?

Election day is November 3rd. Is elaboration really necessary?
During a MAGA rally yesterday in Latrobe PA, the President bragged about how vax R&D normally takes years, but HE managed to cut through the science bureaucracy and get this "done" in mere months.


My latest hardcopy issue just arrived.

The world needs to trust science if vaccines are to prove useful, particularly those being developed to combat coronavirus disease 2019 (COVID-19). That is what makes the recent appearance of highly visible “do-it-yourself” (DIY) vaccine research so morally troubling. It's an obstacle to securing this trust.

As reported in last month's MIT Technology Review, at least 20 people are following the lead of geneticist and entrepreneur Preston Estep to take and promote a homebrew potential vaccine for COVID-19. They have formed a group, Rapid Deployment Vaccine Collaborative (RaDVaC), with the avowed mission of rapidly developing and sharing a vaccine recipe simple enough to be produced and administered by the public...

The DIY effort has no animal or safety trials; no confirmation of safety by closely monitoring healthy volunteers; no dosage studies; no effort to review the proposed science or recruitment of volunteers by an outside, independent ethics review committee; no plan to record all users, to encourage diversity among users, or for systematic follow-up; and no plan to provide help or compensation to anyone harmed by their participation. Moreover, there have been no papers published or data released in peer-reviewed outlets about the vaccine. The research is rife with conflicts of interest in that those making the vaccine are recruiting friends to try it while promoting their actions in the media. They are not selling their vaccine but stand to benefit from attention in the media and any resulting philanthropic support.

There are by most estimates around 200 COVID-19 vaccines in development around the world. Some three dozen are in human trials. A handful have progressed to full-fledged clinical trials. News accounts report that large-scale vaccination efforts without full human safety testing or ethical review are underway in Russia. Given the horrors inflicted on people around the world by the pandemic, it would be reasonable to expect that concerted efforts to find a vaccine would have huge popular support, but that is not the case. Large percentages of people polled in many nations say they will not use or are worried about the safety of a COVID-19 vaccine. Nearly half of all those polled in the United States and United Kingdom in recent months said they would refuse vaccination.

COVID-19 vaccine skepticism has many sources, including doubts about the trustworthiness of safety claims made by government leaders whom many distrust; the perceived inability of government regulatory agencies to maintain independence from political pressure to quickly approve products; and impressions of financial conflicts of interest on the part of those making vaccines.

Trust is the key ingredient in any effort to facilitate a vaccine solution to the current pandemic. Peer-reviewed science transparently assessed in carefully controlled trials by independent experts is the only way to cement that trust. DIY vaccinology is dangerous at a time when nonevidence–based claims of COVID-19 “cures” have done little but sow mistrust of science and public health.

Tangentially apropos, see

Stage IV Metastatic Crazy


"Politicians have rightfully received much of the blame for the COVID carnage, but some scientists and doctors have been giving the rest of us a bad name. When confronted with a new disease, our understanding changes over time, and messages may change. That's good, that's how science should work. Don't let anyone convince you it means that science doesn't know what it's doing. None of these problems are new. Like with everything else, COVID-19 has just exposed issues that already existed, in this case deep problems with science and scientific research."


Read a review in Science. Stay tuned. The incredible Annie Duke (who has a new book coming out soon) recently called me a polymath during an email exchange after learning of my random walk life path. Majorly flattering, but I'm really just an old washed up guitar player still trying to figure out what I'm gonna be when I grow up, LOL.

Anticipated useful triangulation for this new read.


The reading agenda never abates. Coming up shortly.

Ran across the Berman book at SBM. Searching it on Amazon brought me to Dawes. Stay tuned,


Gave Calvin, my new Grandson (7.5 mo) his first Djembe drum lesson this week (we keep him 3 days a week).

His little Cuz, my Great Grandson Kai (2.5 mo, born 7 wks preemie), will be next, once we get to see him (they're in KC).

CCN: 81 Nobel laureates endorse Joe Biden for President

More to come...

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