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Showing posts sorted by relevance for query two cheers for uncertainty. Sort by date Show all posts

Tuesday, November 19, 2019

"Peak human intelligence?" Are we nearing it? Have we passed it?


Recently encountered at The Neurologica Blog:
There is an interesting article at The Conversation asking the question – have humans reached peak intelligence? ... [A]re there ultimate limits to the ability of humans to think, understand, and hypothesize? If so, are we approaching that limit now? ... [I]s there is limit to our ability to manage complexity (as opposed to just comprehending reality)?...
Some might sadly conclude that we've passed peak intelligence, at least in some demographic strata.


Are the tails of the IQ bell curve distribution getting fatter ("kurtosis")? Asymmetrically so (epistemically skewed, with a thin upper tail of "cognitive elites" and a lower "fat tail" comprised of a "Dunning-Kruger" demographic)?

More from Neurologica:
...The article essentially focuses on what we are capable of when thinking clearly, but humans do not always think clearly. We therefore backslide and this also hampers progress. One question is – is the ratio of progress to backsliding changing over historical time? Will this also reach a point of equilibrium?...
...[W]e are also developing artificial intelligence. Whatever you think about the current state and the rate of progress of this endeavor, we are steadily developing more and more intelligent machines, and eventually we will very likely develop general AI with capabilities beyond humans. We may be able to evolve intelligent machines and select them for their ability to solve scientific mysteries...
I will have more to say about "AI" in the foregoing context shortly. See my prior post "Ethical Artificial Intelligence?" for now. Author Flynn Coleman in particular argues that our AI advances may well result in the "birth" of a "new species," one (or more?) with "cognitive" abilities far exceeding those of humans.

Highly recommend you read The Conversation piece in its entirety. Quoting from it:
Will science ever be able to provide all the answers? Human brains are the product of blind and unguided evolution. They were designed to solve practical problems impinging on our survival and reproduction, not to unravel the fabric of the universe. This realisation has led some philosophers to embrace a curious form of pessimism, arguing there are bound to be things we will never understand. Human science will therefore one day hit a hard limit – and may already have done so.
...
Some questions may be doomed to remain what the American linguist and philosopher Noam Chomsky called “mysteries”…

 Well, "two cheers for uncertainty." Two cheers for the "mystery."
If we all knew everything, there would be no point in living, no need for curiosity, for inquiry, for science. It would essentially all be "history" (or, for some people, the "Godhead"). Think about it. Why would you ever even bother to read a book, watch a movie, go to a ball game, take a trip, launch a startup, or whatever? Many uncertainties resolve into verifiable knowledge. Some do not (or have not yet). It's the process of sentient experiential inquiry that really comprises worthwhile living.

Ahhh... what do I know? (Q: Is being God boring? Or does that very question simply reflect a speciocentric, anthropomorphic projective neurosis?)
Tangentially apropos,


LOL.

Back to The Conversation piece:
…Biologically, we are no different than we were 40,000 years ago, but now we know about bacteria and viruses, DNA and molecules, supernovas and black holes, the full range of the electromagnetic spectrum and a wide array of other strange things.

We also know about non-Euclidean geometry and space-time curvature, courtesy of Einstein’s general theory of relativity. Our minds have “reached out” to objects millions of light years away from our planet, and also to extremely tiny objects far below the perceptual limits of our sense organs. By using various tricks and tools, humans have vastly extended their grasp on the world…
Yeah. But, if you're seriously reflective with respect to the import of the word "infinity," the universe will always exceed our "grasp," given our finitude. So, again, Two Cheers for Uncertainty.
"One hopes not only for the courage of one’s convictions, but also for the courage of one’s doubts in a world of dangerously passionate certainties." - the late Eric Sevareid, Not so wild a dream.

CODA

Full disclosure on my "Two Cheers for Uncertainty" riff.

https://www.amazon.com/Rational-Choice-Uncertain-World-Psychology-ebook-dp-B00FBTNQHE/dp/B00FBTNQHE/ref=mt_kindle?_encoding=UTF8&me=&qid=
14.4 Two Cheers for Uncertainty 

Imagine a life without uncertainty. Hope, according to Aeschylus, comes from the lack of certainty of fate; perhaps hope is inherently blind. Imagine how dull life would be if variables assessed for admission to a professional school, graduate program, or executive training program really did predict with great accuracy who would succeed and who would fail. Life would be intolerable—no hope, no challenge. 

Thus, we have a paradox. While we all strive to reduce the uncertainties of our existence and of the environment, ultimate success—that is, a total elimination of uncertainty—would be horrific...

Hastie, Reid. Rational Choice in an Uncertain World (p. 331). SAGE Publications. Kindle Edition.
One of my long-time favorite books.
_____________

More to come...

Monday, May 9, 2016

"Anything that CAN be tracked WILL be tracked." Inevitable Tech Forces That Will Shape Our Future.

"In a few years we’ll have artificial intelligence that can accomplish professional human tasks. There is nothing we can do to stop this. In addition our lives will be totally 100% tracked by ourselves and others. This too is inevitable. Indeed much of what will happen in the next 30 years is inevitable, driven by technological trends which are already in motion, and are impossible to halt without halting civilization. Some of what is coming may seem scary, like ubiquitous tracking, or robots replacing humans. Others innovations seem more desirable, such as an on-demand economy, and virtual reality in the home. And some that is coming like network crime and anonymous hacking will be society’s new scourges. Yet both the desirable good and the undesirable bad of these emerging technologies all obey the same formation principles."

Kevin Kelly, co-founder of Wired.com, an extremely important thinker. I was in the car with NPR on the radio the other day and heard an interview featuring him. Had to look him up forthwith. Interesting man:
My educational background is minimal. I am a college drop out. Instead of going to university, I went to Asia. That was one of the best decisions I ever made. I traveled in the 1970s as a poor, solo photographer in the hinterlands and villages of Asia, between Iran and Japan. I traveled on about US$2,500 per year and came back with 36,000 slides...
His photos are breathtaking. His writing is witty and elegant. His views are at once spot-on and challenging.
"The ongoing scientific process of moving our lives away from the rule of matter and toward abstractions and intangibles can only prepare us for a better understanding of the ultimate abstraction." - Nerd Theology, 1999
Interesting. Prolific, thoughtful observer and writer.

OK, got the interview audio embed link. Thanks, Kevin.
At first glance, Kevin Kelly is a contradiction: a self-described old hippie and onetime editor of hippiedom’s do-it-yourself bible, The Whole Earth Catalog, who went on to co-found Wired magazine, a beacon of the digital age.

In our latest edition of FREAK-quently Asked Questions, Kelly sits down with Stephen Dubner to explain himself; the episode is called “Someone Else’s Acid Trip”...

 
At the moment, I find myself utterly engrossed in his 1994 book "Out of Control. the New Biology of Machines, Social Systems, and the Economic World."

...Images of a machine as organism and an organism as machine are as old as the first machine itself. But now those enduring metaphors are no longer poetry. They are becoming real—profitably real.

This book is about the marriage of the born and the made. By extracting the logical principle of both life and machines, and applying each to the task of building extremely complex systems, technicians are conjuring up contraptions that are at once both made and alive. This marriage between life and machines is one of convenience, because, in part, it has been forced by our current technical limitations. For the world of our own making has become so complicated that we must turn to the world of the born to understand how to manage it. That is, the more mechanical we make our fabricated environment, the more biological it will eventually have to be if it is to work at all. Our future is technological; but it will not be a world of gray steel. Rather our technological future is headed toward a neo-biological civilization.

The triumph of the bio-logic
Nature has all along yielded her flesh to humans. First, we took nature’s materials as food, fibers, and shelter. Then we learned to extract raw materials from her biosphere to create our own new synthetic materials. Now Bios is yielding us her mind—we are taking her logic.

Clockwork logic—the logic of the machines—will only build simple contraptions. Truly complex systems such as a cell, a meadow, an economy, or a brain (natural or artificial) require a rigorous nontechnological logic. We now see that no logic except bio-logic can assemble a thinking device, or even a workable system of any magnitude.

It is an astounding discovery that one can extract the logic of Bios out of biology and have something useful. Although many philosophers in the past have suspected one could abstract the laws of life and apply them elsewhere, it wasn’t until the complexity of computers and human-made systems became as complicated as living things, that it was possible to prove this. It’s eerie how much of life can be transferred. So far, some of the traits of the living that have successfully been transported to mechanical systems are: self-replication, self-governance, limited self-repair, mild evolution, and partial learning. We have reason to believe yet more can be synthesized and made into something new.

Yet at the same time that the logic of Bios is being imported into machines, the logic of Technos is being imported into life.

The root of bioengineering is the desire to control the organic long enough to improve it. Domesticated plants and animals are examples of technos-logic applied to life. The wild aromatic root of the Queen Anne’s lace weed has been fine-tuned over generations by selective herb gatherers until it has evolved into a sweet carrot of the garden; the udders of wild bovines have been selectively enlarged in a “unnatural” way to satisfy humans rather than calves. Milk cows and carrots, therefore, are human inventions as much as steam engines and gunpowder are. But milk cows and carrots are more indicative of the kind of inventions humans will make in the future: products that are grown rather than manufactured.

Genetic engineering is precisely what cattle breeders do when they select better strains of Holsteins, only bioengineers employ more precise and powerful control. While carrot and milk cow breeders had to rely on diffuse organic evolution, modern genetic engineers can use directed artificial evolution—purposeful design—which greatly accelerates improvements.

The overlap of the mechanical and the lifelike increases year by year. Part of this bionic convergence is a matter of words. The meanings of “mechanical” and “life” are both stretching until all complicated things can be perceived as machines, and all self-sustaining machines can be perceived as alive. Yet beyond semantics, two concrete trends are happening: (1) Human-made things are behaving more lifelike, and (2) Life is becoming more engineered. The apparent veil between the organic and the manufactured has crumpled to reveal that the two really are, and have always been, of one being. What should we call that common soul between the organic communities we know of as organisms and ecologies, and their manufactured counterparts of robots, corporations, economies, and computer circuits? Icall those examples, both made and born, “vivisystems” for the lifelikeness each kind of system holds.

In the following chapters I survey this unified bionic frontier. Many of the vivisystems I report on are “artificial”—artifices of human making—but in almost every case they are also real—experimentally implemented rather than mere theory. The artificial vivisystems Isurvey are all complex and grand: planetary telephone systems, computer virus incubators, robot prototypes, virtual reality worlds, synthetic animated characters, diverse artificial ecologies, and computer models of the whole Earth.

But the wildness of nature is the chief source for clarifying insights into vivisystems, and probably the paramount source of more insights to come...

The vivisystems I examine in this book are nearly bottomless complications, vast n range, and gigantic in nuance. From these particular big systems I have appropriated unifying principles for all large vivisystems; I call them the laws of god, and they are the fundamentals shared by all self-sustaining, self-improving systems.
As we look at human efforts to create complex mechanical things, again and again we return to nature for directions. nature is thus more than a diverse gene bank harbor- ing undiscovered herbal cures for future diseases—although it is certainly this. nature is also a “meme bank,” an idea factory. Vital, postindustrial paradigms are hidden in every jungly ant hill. The billion-footed beast of living bugs and weeds, and the aboriginal human cultures which have extracted meaning from this life, are worth protecting, if for no other reason than for the postmodern metaphors they still have not revealed. destroying a prairie destroys not only a reservoir of genes but also a treasure of future metaphors, insight, and models for a neo-biological civilization... [pp. 6-8]
In a month, I'll be downloading and reading his forthcoming title.


I'll be triangulating a lot of Kevin Kelly with my prior posts about "AI." e.g., "AI vs IA: At the cutting edge of IT R&D."

A bonus for watching the complete Kevin Kelly SXSW talk was that it was followed in my YouTube feed with one by the equally compelling Douglas Rushkoff, who I've cited on this blog in prior posts. See here as well.



If you're too busy (or too lazy) to obtain and read the Rushkoff book, his SXSW talk will likely suffice as Cliff Notes.

I also recommend you triangulate all of this stuff with Paul Mason's excellent book "Postcapitalism." See "The future of health care, continued. Where will economics come in?"

So coming back around to the core tech thing -- Health IT -- see my May 2nd post "Better, Smarter, and Healthier" Really?" Wherein Robin Farmanfarmian waxes rhapsodic over the nascent wave of 24/7 ubiquitous digital sensing technologies.

"Free Beer Tomorrow?"
__

UPDATE

Interesting link on Kevin Kelly's site:

The Anecdote is the Antidote for What Ails Modern Medical Science by John R. Adler, Jr. M.D. It’s hard to imagine anybody being more of a medical insider than Dr. John R. Adler, the founding editor of Cureus. Adler has a Harvard medical degree, served his residency at Massachusetts General hospital, and is a Stanford professor of neurosurgery, as well as founding CEO of a leading radiation oncology company, Accuray.  This makes it especially heartening that Dr. Adler is now focused on opening up medical research literature to important kinds of evidence that have often been ignored: the anecdote and the case report.  Quote: “The altruism that is supposed to drive the publication of scientific research has been almost entirely co-opted by the peculiar needs of academic promotion and tenure, as well as the pecuniary demands of the scholarly publishing industry; the public good of medical knowledge has been reduced to a mere after-thought by both academia and the publishing industry.”
__

THURSDAY UPDATE

apropos of the foregoing AI/IA/Robotics riff, an across this article this morning on Medium:
Why You Will Soon Be Sharing Your Deepest Secrets With A Robot: This will be the largest cognitive leap in human history.
Note the author byline:


I guess now resumes will be increasingly replete with how many IPO exits one has been "associated" with, for what dollars amounts.

Lordy.

Another cool article I first noticed in a Medium.com cross-post: "Three Years in San Francisco."

Then there's Edge.org. Like I don't already have enough to read. to wit:

Weighing in from the cutting-edge frontiers of science, today’s most forward-thinking minds explore the rise of “machines that think.”

Stephen Hawking recently made headlines by noting, “The development of full artificial intelligence could spell the end of the human race.” Others, conversely, have trumpeted a new age of “superintelligence” in which smart devices will exponentially extend human capacities. No longer just a matter of science-fiction fantasy (2001, Blade Runner, The Terminator, Her, etc.), it is time to seriously consider the reality of intelligent technology, many forms of which are already being integrated into our daily lives. In that spirit, John Brockman, publisher of Edge. org (“the world’s smartest website” – The Guardian), asked the world’s most influential scientists, philosophers, and artists one of today’s most consequential questions: What do you think about machines that think?
I find it interesting that the usual list of allusively admonitory movie citations misses this one:


The self-repairing autonomous "Mark 13" warrior robot. A gruesome, dystopian cult flick. One of my faves.

Also up amid the never-diminishing book stash:


Additionally on deck: "Two cheers for uncertainty." What the hell does that mean? Isn't "science" (in particular medical science and its bedrock IT foundation) all about reducing uncertainty?

For now, a bit of Kevin Kelly tease on the topic:
Letting go to win
As Moses tells the story, on the sixth day of creation, that is at the eleventh hour of a particularly frantic creative bout, the god kneaded some clayey earth and in an almost playful gesture, crafted a tiny model to dwell in his new world. This god, Yahweh, was an unspeakably mighty inventor who built his universe merely by thinking aloud. He had been able to do the rest of his creation in his head, but this part required some fiddling. The final hand-tuned model—a blinking, dazed thing, a “man” as Yahweh called him—was to be a bit more than the other creatures the almighty made that week.

This one was to be a model in imitation of the great Yahweh himself. In some cybernetic way the man was to be a simulacra of Yahweh.

As Yahweh was a creator, this model would also create in simulation of Yahweh’s creativity. As Yahweh had free will and loved, this model was to have free will and love in reflection of Yahweh. So Yahweh endowed the model the same type of true creativity he himself possessed.

Free will and creativity meant an open-ended world with no limits. Anything could be imagined, anything could be done. This meant that the man-thing could be creatively hateful as well as creatively loving (although Yahweh attempted to encode heuristics in the model to help it decide).

Now Yahweh himself was outside of time, beyond space and form, and unlimited in scope—ultimate software. So making a model of himself that could operate in bounded material, limited in scale, and constrained by time was not a cinch. By definition, the model wasn’t perfect.

To continue where Moses left off, Yahweh’s man-thing has been around in creation for millennia, long enough to pick up the patterns of birth, being, and becoming. A few bold man-things have had a recurring dream: to do as Yahweh did and make a model of themselves—a simulacra that will spring from their own hands and in its turn create novelty freely as Yahweh and man-things can.

So by now some of Yahweh’s creatures have begun to gather minerals from the earth to build their own model creatures. Like Yahweh, they have given their created model a name. But in the cursed babel of man-things, it has many designations: automata, robot, golem, droid, homunculus, simulacra.

The simulacra they have built so far vary. Some species, such as computer viruses, are more spirit than flesh. Others species of simulacra exist on another plane of being—virtual space. And some simulacra, like the kind marching forward in SIMNET, are terrifying hybrids between the real and the hyperreal.

The rest of the man-things are perplexed by the dream of the model builders. Some of the curious bystanders cheer: how wonderful to reenact Yahweh’s incomparable creation! Others are worried; there goes our humanity. It’s a good question. Will creating our own simulacra complete Yahweh’s genesis in an act of true flattery? Or does it commence mankind’s demise in the most foolish audacity?

Is the work of the model-making-its-own-model a sacrament or a blasphemy?

One thing the man-creatures know for sure: making models of themselves is no cinch.

The other thing the man-things should know is that their models won’t be perfect, either. Nor will these imperfect creations be under godly control. To succeed at all in creating a creative creature, the creators have to turn over control to the created, just as Yahweh relinquished control to them.

To be a god, at least to be a creative one, one must relinquish control and embrace uncertainty. Absolute control is absolutely boring. To birth the new, the unexpected, the truly novel—that is, to be genuinely surprised—one must surrender the seat of power to the mob below.

The great irony of god games is that letting go is the only way to win.
[Kevin Kelly, Out of Control, pp. 219-220]
"...one must relinquish control and embrace uncertainty. Absolute control is absolutely boring."

From my stacks:

Two cheers for uncertainty
Imagine a life without uncertainty. Hope, according to Aeschylus, from the lack of certainty of fate; perhaps hope is inherently blind. Imagine how dull life would be if variables assessed for admission to professional school, graduate program, or executive training program really did predict with great accuracy who would succeed and who would fail. Life would be intolerable — no hope, no challenge.

Thus we have a paradox. Although we all strive to reduce the uncertainties of our existence and of the environment, ultimate success — that is, a total elimination of uncertainty — would be horrific...

[even] knowing pleasant outcomes with certainty would also detract from life's joy. An essential part of knowledge is to shrink the domain of the unpredictable. But although we pursue this goal, its ultimate attainment would not be at all desirable.

Living with uncertainty
Without uncertainty, there would be no hope, no ethics, and no freedom of choice. It is only because we do not know what the future holds for us (e.g., the exact time and manner of our own death) that we can have hope. It is only because we do not know exactly the results of our choices that our choices can be free and to compose a true ethical dilemma. Moreover, most of us are aware that there is much uncertainty in the world, and one of our most basic choices is whether we will accept that uncertainty is a fact or try to run away from it. Those who choose to deny uncertainty invent a stable world of their own. Such people's natural desire to reduce uncertainty, which may be basic to the whole cognitive enterprise of understanding the world, is taken to the extreme point where they believe that uncertainty does not exist. The statisticians definition that an optimist is "someone who believes that the future is uncertain" is not as cynical as it may at first appear to be [Hastie & Dawes, Rational Choice in an Uncertain World, 2001, pp. 326 -- 328].
I once appropriated this idea for some song lyrics:
What's there to see
In the Land of the Blind?
Where they're all 20-20,
Having made up their minds.
Well, Two Cheers for the Mystery,
Otherwise, it's all History.
If it's all just so clear,
What're we still doin here?
Maybe one day I'll finish that song.

I'm not sure I'm driving toward any clear point here. It's just about the broad implications of AI science and technology, and the uncertainty regarding where they will lead us, given that notable people like Hawking, Boostrom, Musk, and Bill Gates have voiced concerns -- concerns that Kevin Kelly has done his best to counter, e.g., "Why I Don't Worry About a Super AI."
NOTE: If you can get through Jaron Lanier's ramblingly obtuse "The Myth of AI," beginning at about halfway down the long web page are a raft of illuminating expert comments on the topic. Well worth your time.
At this point it looks to me that AI will be more "IA" in the health care domain -- "Intelligence Augmentation" (recall Larry Weed?) that helps the clinicians sift through the otherwise increasingly unmanageable torrents of data they face when trying to arrive at accurate dx's and efficacious px's and tx's. to wit,
The Rise of the Chief Cognitive Officer

...Toby Cosgrove, the CEO of the Cleveland Clinic stated “It may sound odd, but technology like Watson will make healthcare less robotic and more human.” The reasoning behind putting an AI through a version of medical school is that human physicians can’t possibly read and process the exponentially growing volumes of clinical trials, medical journals, and individual cases available in the digital domain. A computer that digests them can transform them into useful support options for care of a patient. Furthermore humans can’t be a part of every case and learn from every physician. But by combining a human with the capacity of a computer as a physician’s assistant, physicians can focus on the many things that they are uniquely able to do in the complex domain of medicine. This includes the critical conversations with patients and their families.

In short a more human physician interaction can be made by sharing the workload between man and machine. The upshot of the shift to cognitive clinical decision support is that we will likely increasingly see an evolving marriage and interdependency between the worlds of AI (Artificial Intelligence) thinking and human provider thinking within medicine...
The root word for cognitive in Latin is “cogn” which means “to learn, know.” It tends to be an active requirement for success in modern medicine with ideas such as ‘the learning health system’ — and the modern learning health system is typically able to learn and know things because algorithms do a chunk of the learning that people can’t scale to do.

At the moment I don’t work within a health system. Because I am focusing on Cognitive Computing I am considering declaring myself the Chief Cognitive Officer and taking over establishing systems of anything related to thinking and knowledge. I wonder if anyone will stop me? Maybe the job of the chief cognitive officer should be the CEO? I’d say so but ‘executive’ implies decisions. Thinking isn’t always about big decisions but about the tools that can be used to make the millions of little decisions needed for every interaction to generate value. Someone has to make this next generation stuff work.

At least that is how my AI and I think.
The Robot Will See You Now?

CODA

On another aspect of cutting edge technology,

 
Top scientists hold closed meeting to discuss building a human genome from scratch

Over 130 scientists, lawyers, entrepreneurs, and government officials from five continents gathered at Harvard on Tuesday for an “exploratory” meeting to discuss the topic of creating genomes from scratch — including, but not limited to, those of humans, said George Church, Harvard geneticist and co-organizer of the meeting.

The meeting was closed to the press, which drew the ire of prominent academics...


The topic is a heavy one, touching on fundamental philosophical questions of meaning and being. If we can build a synthetic genome — and eventually, a creature — from the ground up, then what does it mean to be human?

“This idea is an enormous step for the human species, and it shouldn’t be discussed only behind closed doors,” said Laurie Zoloth, a professor of religious studies, bioethics, and medical humanities at Northwestern University...
'eh?
____________

More to come...

Tuesday, January 13, 2015

Thank you, Jonathan Bush and athenahealth


And, thanks to everyone who attended. In particular the inspiring Alexandra Drane. I met Alex last September at Health 2.0 in Santa Clara, after seeing her moderate the "Unmentionables Panel."

I shlepped my big cameras last night, but decided it would be inappropriate to do any photography, like I do at many Health IT events. Nor will I ID any of the other attendees. Suffice it to say that it was A-List company. It was a freewheeling night of robust and frank discussion. I am honored to have been invited to sit among and interact with so many  supersmart and accomplished people.

The dinner topic was about risk and failure, and what we can learn from them that helps us be more likely to be successful long-term. We, each in turn, had to take the floor, cite who were were and what we did, and recount one of our biggest failures.

Mine was a doozy. Had nothing to do with health care or business more broadly. It was about the time in the mid-1980s when I inadvertently blew up Lee Greenwood's University of Tennessee Homecoming game nationally-televised performance (ABC-TV) of his hit song "God Bless the USA." I was working with the Neyland Stadium field audio contractor, manning the sound board at the 50 yard line. Accidentally knocked out the audio mixer atop the rack of slave amps and outboard signal processing gear that drove the array of massive speaker sets we always ringed around the breadth of the stadium track. We lost the first 45 seconds of his performance before we found and fixed the simple problem. Someone, probably me, had bumped the amber on/off rocker switch on the mixer unit. In the bright mid-day sunlight, none of us could see that it was off. Given its criticality and vulnerability, it should have been hard-soldered "on" so that you'd have to pull the plug to shut it down.


I got fired. You fuck up in front of 100,000 stadium fans and millions more on national TV, there's no "fix the process, not the blame." They had to physically restrain the UTK marching band conductor 'Doc" Julian from assaulting me in full view of the sell-out crowd. Seriously; he was a legendary neck-vein-popping hothead (to state it politely) in the best of circumstances. He wanted a piece of me. I'd probably have gone to jail to boot had we tangled.

I was aghast. Worse, this was my alma mater. My crewmates were my friends. The crew manager, Alan, was the keyboard player in our band.

So, yeah. Painful to publicly recount that. I could have cited the time my little Knoxville bootstrap A/V company got blindsided by a material structural change in the high school ACT Exam that was the topic of our flagship "exam cram" video product -- a revision that rendered my entire fulfillment center inventory obsolete in an instant. I could have spoken of the time I presented one of my technical papers at an EPA Radiochemistry Technical Conference in Oak Ridge, only to get mercilessly, humiliatingly skewered during the Q&A. Or, I could have recounted the time in 1992 when the West Knoxville entreprenuerial industrial diagnostics company, wherein I served as the Technical Editor/Writer, lost a microprocessor assembly language FFT algorithm patent infringement civil suit jury decision we'd been assured by management would never happen, and regarding which we had zero contingency plan.

Nahhhh...
__

Someone brought up Daniel Kahneman last night. Yeah, the relative functions and merits of "Fast and Slow Thinking." Cognitive heuristics and attendant bias liabilities. I have all of his books.

Risk and failure. Cognition and contingency. Expertise and concomitant overconfidence.

From the lyrics in one of my songs, "What Do I Know?"

What's there to see
In the Land of The Blind,
Where they're all 20-20,
Having made up their minds?
Well, two cheers for The Mystery,
Otherwise, it's all history.
If it's all just so clear,
What're we still doin' here?

LOL. I shamelessly ripped that idea off from Chapter 14 of the Hastie-Dawes book "Rational Choice in an Uncertain World."

14.4 Two cheers for uncertainty

Imagine a life without uncertainty. Hope, according to Aeschylus, comes from the lack of certainty of fate; perhaps hope is inherently blind. Imagine how dull life would be if variables assessed for admission to a professional school, graduate program, or executive training program really did predict with great accuracy who would succeed and who would fail. Life would be intolerable – no hope, no challenge.

Thus we have a paradox. Although we all strive to reduce the uncertainties of our existence and of the environment, ultimate success – that is, a total elimination of uncertainty — would be horrific... [pg 326]
Indeed. Imagine that we could know everything? What would be the point of even living out our human lives?

I trained at the outset of my white collar career in forensic analytical science. I'm a hardass when it comes to hewing to the scientific method. But, as I said last night, frankly, the more I study and learn, the less I feel I know.

"If you're not confused, you've not been paying attention."

apropos, 
Scientific progress is like mountain climbing: the higher you climb, the more you know, but the wider the vistas of ignorance that extend on all sides...

I have begun to imagine human knowledge and ignorance as tracing a graph of asymptotic divergence, such that with every increase in knowledge, there occurs a greater increase in ignorance. The result is that our ignorance always exceeds our knowledge, and the gap between the two grows infinitely greater, not smaller, as infinite time passes.

Ignorance was a great human breakthrough, perhaps the greatest of all, for until our prehistoric but anatomically modern ancestors could tell the difference between ignorance and knowledge, how could they know they knew anything? The actual date, the actual occasion, the actual individual who first became conscious of the difference between knowing and not knowing are all beyond historical recovery, but some such moment surely had to have come long before the invention of writing. And how different was that moment in the life span of the human species from this moment?...


One thing [Bertrand] Russell was right about is that Earth and the human species alike have finite life expectancies: “The whole temple of man’s achievement must inevitably be buried beneath the debris of a universe in ruins.” You may die never having learned the one fact that would have changed everything for you. In just the same way, extinction may befall the human species with key questions still unanswered and perhaps even unasked. And as that moment nears, will science have been superseded by something that differs from it as much as it differs from philosophy or philosophy from religion? When we reflect on how slightly, on the one hand, our genome differs from that of the chimpanzee and how greatly, on the other hand, our knowledge surpasses that of our genetic cousin, can we not imagine that a further minor genetic alteration might bring into existence a being whose knowledge and modes of inquiry dwarf ours as much as ours dwarf those of the chimpanzee?...
Ponder that last sentence in particular. From Jack Miles' "Why God Will Not Die."

"Singularity," anyone?

@08:54 “We are now actually re-programming biology. It’s a whole different paradigm for health and medicine."
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Next up, on Thursday, "Health 2.0 WinterTech Conference."


Another fun, informative day in the city. My shutters will be a-clickin' this time.

WEDNESDAY NEWS UPDATES
Athenahealth Moves Into Hospital Market With Acquisition Of Atlanta Startup RazorInsights

Athenahealth  is getting into the hospital market. The company which provides cloud-based billing and electronic health record software services to nearly 60,000 office-based medical professionals bought RazorInsights, an Atlanta start-up that sells EHRs to rural and community hospitals. “It gives us a head start. We’re paying a few million dollars to skip the prototyping,” says Jonathan Bush, athenahealth’s CEO.

Taking baby steps is a prudent approach. The outpatient to inpatient transition via acquisitions can be treacherous. Allscripts watched its fortunes dip following its purchase of Eclipsys, as it struggled to integrate the two sides.

With the exception of its $293 million acquisition of Epocrates , a mobile drug reference tool for physicians, athenahealth has a history of making small purchases and quickly assimilating them into its branded suite of software. In 2008, it bought MedicalMessaging.net for nearly $8 million, and folded it into its patient portal. In 2011, it purchased Proxsys for $28 million; it is now part of its care coordination and population health management offering. “This [RazorInsights] is not a bolt on,” says Jeremy Delinsky, athenahealth’s chief product officer...
Below, having just spent an evening in the company of a number of venture capital execs at Jonathan's dinner, I found this interesting.
Does VC involvement undermine interoperability?
While venture capitalists have long been involved in healthcare, the more than $6.5 billion reported to have been invested last year raises the stakes for the VC community and the healthcare industry. New healthcare companies and ventures, flush with investor cash at such a high level, are in the midst of a happy honeymoon phase.

But things could get difficult quickly for VC-backed health IT startups. Healthcare is no longer just another vertical for institutional investors. Now, it's a major bet dominating many firms' portfolios, which means they'll want a competitive advantage even more than they have before. 

Unfortunately, VC investors and the healthcare world want different things from health IT. In theory, smart VCs know that the health IT industry is pushing for interoperability, but in practice, they're likely to resist any solution that doesn't give startups a proprietary edge...
Yeah. "Opacity = Margin." Rather axiomatic to private markets, all the lovely allusions to "transparency" notwithstanding. Another problem I see, apropos of the theme of Jonathan's dinner topic Monday night, goes to the increasing compression of the entrepreneurial success/failure cycle. Moreover, in that regard, I have to wonder about VCs' requisite, problematic motives: these firms are not charged with beneficently "transforming healthcare" -- adding "value" writ large -- their necessary priorities go to "valuation," -- making money, irrespective of any net benefit to society. The "Built to Flip" IPO path remains solidly with us. Social value is swell if it happens as one result, but it cannot be a VC priority. "Fail early, fail often," romantically charming as it may sound as a theoretical motivational ideal for young entrepreneurs, seems to me fundamentally at odds with the venture capital imperative.

CODA


After having had dinner with Jonathan and his posse Monday night, and now seeing this, I have to say, I'm rather impressed.

Relevant to many of Jonathan's points in the video:
Clinical Documentation in the 21st Century: Executive Summary of a Policy Position Paper From the American College of Physicians
Thomson Kuhn, MA; Peter Basch, MD; Michael Barr, MD, MBA; Thomas Yackel, MD, MPH, MS, for the Medical Informatics Committee of the American College of Physicians

In the past decade, medical records have become increasingly synonymous with electronic health records (EHRs). However, although “EHR” is the current term of art used to describe computer-based systems that perform a broad range of functions related to documenting and managing patient care, this will not always be the case. Similarly, clinical documentation's definition has grown to encompass more than just physician notes. Existing technology, such as registries, portals, connected home monitoring devices, and provider- and patient-controlled mobile devices, as well as technology not yet in use or even built, is likely to integrate with or possibly even replace the EHR (as currently conceptualized) as a primary vehicle for viewing and recording clinical documentation. Although the term “EHR” is used throughout this paper, the issues addressed could reasonably apply to any future technology-enabled system of clinical documentation.

This position paper reviews the current and emerging purposes of clinical documentation, the drivers that may influence or distract from these purposes, and the opportunities and challenges that have arisen from EHRs. We believe that physicians must help define and prioritize the many important roles that clinical documentation serves today. Therefore, this paper proposes a set of guiding principles and actions that can be taken by clinicians, provider institutions, technology vendors, government regulators, payers, and other interested groups to improve the quality and value of clinical documentation and to better use this documentation to improve care.

The primary goal of EHR-generated documentation should be concise, history-rich notes that reflect the information gathered and are used to develop an impression, a diagnostic and/or treatment plan, and recommended follow-up. Technology should facilitate attainment of these goals in the most efficient manner possible without losing the humanistic elements of the record that support ongoing relationships between patients and their physicians...


Summary
Electronic health records should be leveraged for what they can do to improve care and documentation, including effectively displaying prior information that shows historical information in rich context; supporting critical thinking; enabling efficient and effective documentation; and supporting appropriate and secure sharing of useful and usable information with others, including patients, families, and caregivers. These features are unlikely to be optimized as long as the format and content of clinical documentation are primarily based on coding and other regulatory requirements. Furthermore, under these circumstances, EHRs lose much of their potential to improve care and documentation and instead are relegated to doing nothing that could not be done with paper records—only less efficiently.

We are in danger of repeating history by overstructuring the clinical record and overloading it with extraneous data (2). Physicians must learn to leverage the enormous and growing capabilities of EHR technology without diminishing or devaluing the importance of narrative entries. Failure to do so will inevitably influence the way we think and teach, to the detriment of patient care.

Cooperation is needed among industry health care providers, health care systems, government, and insurers to continue to improve the documentation. We must work together to fundamentally change the EHR from a passive recipient of information to an active virtual care team member.
Full paper link here. Between the opening paragraphs and the summary is a wealth of detail. (Nice that they cite Dr. Weed.) The "policy recommendations" sections are replete with the usual relatively noncontroversial "shoulds," but don't delve into the "hows." That is the tough part.

Relatedly, reported by Politico:
“HUMAN FACTOR” PROBLEMS PERSIST WITH EHRs: Although interoperability is the buzzword of health IT in 2015, another word persists: usability. Physicians still rage at the awkwardness of their electronic health records, whose improvement is one of the top objectives of the federal health IT strategic plan, Arthur Allen reports. The plan lists “encourag[ing] the application of human factors, health literacy, and user-centered design” of EHRs as a top objective — along with renewed attention to the “safe use” of health IT. Don’t count on the government to do much about it. Andrew Gettinger, acting director of ONC’s office of clinical quality and safety, sees the invisible hand playing the major role. “There is going to be more and more success for software that really demonstrates better clinician acceptance,” he said in an interview. “I think it would be speculative to talk about regulatory approaches.” Some experts attribute usability problems to the lack of human factors engineers in health IT. American universities have relatively few experts or programs for students, and EHR vendors, including large ones, often do not employ any. EHRs have led to a dramatic shift in the way doctors spend their time, and one the biggest concerns is the mental stress they create, says Raj Ratwani, scientific director at the National Center for Human Factors, located in the futuristic Intelsat building in Northwest Washington, DC. He followed 14 doctors from just before a new EHR was installed in their emergency department until four months later. After implementing the EHR, doctors spent 20 percent more of their time doing two or three tasks at the same time. Some hospitals say the HITECH Act was too rushed and vendors didn’t take human factors into account when designing EHRs.
"National Center for Human Factors"?

The National Center for Human Factors in Healthcare brings together a diverse set of human factors experts with clinical experts to improve quality, efficiency, reliability, and safety in healthcare. A part of the MedStar Institute for Innovation (MI2) and the MedStar Health Research Institute (MHRI), the Center’s home and “research lab” is MedStar Health, a $4.5B not-for-profit healthcare organization with 10 hospitals and 20 diversified healthcare organizations, the largest healthcare provider in the Baltimore & Washington DC region.

Interesting.
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More to come...

Saturday, May 4, 2019

Another "Omics" in the health care space

My wife just passed along this Washington Post article to me.
"Doctors who are kind have healthier patients who heal faster, according to new book"
I bought and downloaded the book. Thanks, Cheryl. Add another branch to the "Omics," 'eh?

Stay tuned.


From the Amazon blurb:
A 34-year-old man fighting for his life in the Intensive Care Unit is on an artificial respirator for over a month. Could it be that his chance of getting off the respirator is not how much his nurses know, but rather how much they care?

A 75-year-old woman is heroically saved by a major trauma center only to be discharged and fatally struck by a car while walking home from the hospital. Could a lack of compassion from the hospital staff have been a factor in her death?

Compelling new research shows that health care is in the midst of a compassion crisis.
But the pivotal question is this: Does compassion really matter?

In Compassionomics: The Revolutionary Scientific Evidence that Caring Makes a Difference, physician scientists Stephen Trzeciak and Anthony Mazzarelli uncover the eye-opening data that compassion could be a wonder drug for the 21st century.

Now, for the first time ever, a rigorous review of the science - coupled with captivating stories from the front lines of medicine - demonstrates that human connection in health care matters in astonishing ways. Never before has all the evidence been synthesized together in one place.

You will see compelling evidence that:

  • Compassion has vast benefits for patients across a wide variety of conditions
  • Missed opportunities for compassion can have devastating health effects
  • Compassion can help reverse the cost crisis in health care
  • Compassion can be an antidote for burnout among health care providers
  • 40 seconds of compassion can save a life
After seeing all the evidence, the answer is crystal clear: Compassion matters...in not only meaningful but measurable ways.
We shall see. From the Foreword by Senator Cory Booker:
We are often led to believe that sentiments like compassion, love and kindness are expressions of weakness rather than signs of strength. And we are often all too ready to give in to the false belief that meanness somehow equates to toughness and that empathy is empty of power... [Kindle location 168]
"...meanness somehow equates to toughness..." Remind you of anyone of late? Hmmm...

I look forward to studying this book. I have to think that one reason I sailed through my SAVR px last August was the empathic, compassionate care of my cardiac surgeon and his team.

I left a comment under the WaPo article.
There is good scientific evidence that prosocial behaviors--up to and including the altruistic (sorry, Ayn Rand)--have evolutionary "adaptive utility." See, e.g., Tomasello's "A Natural History of Human Morality." Which simply makes sense when you fully reflect on it. "Nature may be red in tooth and claw, but it is not merely so." - Sam Harris. 

I just bought the book and will report on it at KHIT.org ASAP.
ONE FURTHER NOTE

The author of the WaPo article has a heavy duty Sheet and a new book out.


"The science of happiness?" There's that word "science" again. More stuff to study and evaluate.

ERRATUM

"Physicists, philosophers debate whether research can ever solve certain mysteries of the universe—and the human mind"
Well, duhhh.. Seriously? Scientific American, no less. My favorite Hastie & Dawes quote: "Two Cheers for Uncertainty."

C'mon, think about it.
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More to come...